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MF-300: Sarcopenia
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Posters and Publications
Posters
ICFSR 2025: MF-300 (15-PGDH Enzyme Inhibitor) Accelerates Recovery of Muscle Force in a Mouse Model of Nerve Injury
ICFSR 2025: MF-300 (15-PGDH Enzyme Inhibitor) Reverses Age-Related Muscle Weakness in Mice by Restoring Muscle Quality
GSA 2024: MF-300 (15-PGDH Enzyme Inhibitor) Reverses Age-Related Muscle Weakness in Mice by Restoring Muscle Quality
CureSMA 2023: Efficacy of MF 300 in Preclinical Models of Spinal Muscular Atrophy
Publications
Prostaglandin E2 is essential for efficacious skeletal muscle stem-cell function, augmenting regeneration and strength
Inhibition of prostaglandin-degrading enzyme 15-PGDH rejuvenates aged muscle mass and strength
Regeneration of neuromuscular synapses after acute and chronic denervation by inhibiting the gerozyme 15-prostaglandin dehydrogenase